Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741313 | 0.82 | NPSR1 (0.55) | SMN1; SMN2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL10741723 | 0.80 | CYP3A4 (0.50) | SMN1; SMN2KDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL10735118 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL10744234 | 0.79 | PDE7A (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10741060 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL877861 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL10739938 | 0.68 | TDP1 (0.57) | SMN1; SMN2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL10740253 | 0.68 | TUBB4A (0.52) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL10737433 | 0.67 | TDP1 (0.64) | SMN1; SMN2ALDH1A1KDM4ETDP1NPSR1 | |
| SCHEMBL10733928 | 0.65 | PDE7A (0.49) | SMN1; SMN2ALDH1A1NPSR1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |