SCHEMBL1074168

SCHEMBL1074168

C/C(=C\COCc1ccccc1)CC/C=C(\C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.52
LSS P48449 2/20 0.47
PPARG P37231 1/20 0.45
BACE1 P56817 1/20 0.43
ALDH1A1 P00352 1/20 0.41
ICMT O60725 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074171 1.00 TRPV1 (0.52) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL11041918 0.99 TRPV1 (0.51) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL11038479 0.99 TRPV1 (0.51) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL11045642 0.99 TRPV1 (0.51) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL11041922 0.99 TRPV1 (0.51) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL11045639 0.99 TRPV1 (0.51) TRPV1LSSPPARGBACE1ALDH1A1
SCHEMBL20521373 0.87 ALDH1A1 (0.50) ALDH1A1
SCHEMBL466109 0.87 ALDH1A1 (0.50) ALDH1A1
SCHEMBL795298 0.85 TRPV1 (0.60) TRPV1LSSALDH1A1ICMT
SCHEMBL795297 0.85 TRPV1 (0.60) TRPV1LSSALDH1A1ICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1797953-B1 PROCESS FOR PRODUCING OXYGENIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2011-01-05 EP disclosed
CN-1988955-B Method for producing oxygen-containing compound SUMITOMO CHEMICAL CO 2010-09-29 CN disclosed
US-20080064898-A1 Method for Producing Oxygen-Containing Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-13 US disclosed
US-7276622-B2 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-02 US disclosed
CN-1988955-A Method for producing oxygen-containing compound SUMITOMO CHEMICAL CO (JP) 2007-06-27 CN disclosed
EP-1797953-A1 PROCESS FOR PRODUCING OXYGENIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-06-20 EP disclosed
US-20060173221-A1 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-03 US disclosed
EP-1609777-A1 METHOD FOR PRODUCING OXYGEN-CONTAINING COMPOUND Sumitomo Chemical Company, Limited (JP) 2005-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064898-A1 Method for Producing Oxygen-Containing Compound AOC2, AOX1, CAT TRPV1 2985/4885LSS 774/4885PPARG 718/4885
US-20060173221-A1 Method for producing oxygen-containing compound GPX4, DUOX2, SCO2 TRPV1 3320/4885LSS 494/4885PPARG 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.