SCHEMBL1074244

SCHEMBL1074244

CCC(CCOC(=O)c1cccc(Cl)c1)OC(=O)c1cccc(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.43
PRKCA P17252 2/20 0.43
PRKCD Q05655 2/20 0.43
BCHE P06276 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14334871 0.84 HPGD (0.54) CHRM2CHRM4CHRM1CHRM3RAB9A
SCHEMBL14399225 0.84 CHRM2 (0.49) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL1081918 0.83 GAA (0.51) CHRM1ALDH1A1PRKCAPRKCDLMNA
SCHEMBL5081311 0.83 LMNA (0.60) RAB9AALDH1A1PRKCAPRKCDLMNA
SCHEMBL6057367 0.82 CHRM2 (0.52) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL14335422 0.81 HPGD (0.45) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL14334936 0.80 HPGD (0.45) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL14334771 0.80 HPGD (0.44) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL6057368 0.80 LMNA (0.64) CHRM2CHRM4CHRM1CHRM3L3MBTL1
SCHEMBL810821 0.80 L3MBTL1 (0.57) CHRM2CHRM4CHRM1CHRM3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-9951157-B2 Spherical carriers for olefin polymerization catalyst, catalyst components, catalyst, and preparation methods therefor CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-04-24 US claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20160251457-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-01 US claimed
EP-3059263-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-03-26 US disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9951157-B2 Spherical carriers for olefin polymerization catalyst, catalyst components, catalyst, and preparation methods therefor CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-04-24 US disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-2489685-B1 Process for preparing a catalyst component for olefin polymerization CHINA PETROLEUM & CHEM CORP (CN) 2017-08-30 EP disclosed
EP-2454290-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM China Petroleum & Chemical Corporation (CN) 2012-05-23 EP disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
WO-2011006278-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-01-20 WO disclosed
EP-2185600-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE Dow Global Technologies Inc. (US) 2010-05-19 EP disclosed
WO-2009029447-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-03-05 WO disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom MSMO1, SCO2, RTF1 CHRM2 104/4885CHRM4 584/4885CHRM1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.