SCHEMBL6057367

SCHEMBL6057367

CC(C)CCOC(=O)c1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.52
CHRM4 P08173 1/20 0.52
CHRM1 P11229 1/20 0.52
CHRM3 P20309 1/20 0.52
ALDH1A1 P00352 3/20 0.51
PKM P14618 2/20 0.51
GAA P10253 2/20 0.51
KDM4E B2RXH2 1/20 0.51
KMT2A Q03164 1/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
RAB9A P51151 1/20 0.49
PARP1 P09874 1/20 0.45
SLC6A2 P23975 2/20 0.44
CHRNA1 P02708 1/20 0.44
CHRNG P07510 1/20 0.44
ITGA5 P08648 1/20 0.44
CHRNB1 P11230 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5371533 0.89 KMT2A (0.58) ALDH1A1PKMGAAKDM4EKMT2A
SCHEMBL14399225 0.87 CHRM2 (0.49) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL810821 0.85 L3MBTL1 (0.57) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL6057293 0.84 CHRM2 (0.55) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL14335175 0.84 HPGD (0.51) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL6057368 0.83 LMNA (0.64) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL811440 0.82 TDP1 (0.61) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL1074244 0.82 CHRM2 (0.47) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL14334938 0.82 HPGD (0.46) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL28280197 0.82 ADRB2 (0.56) ALDH1A1PKMGAAKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1159315-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
CN-1214049-C Process for producing ethylene/olefin interpolymers EASTMAN CHEM CO (US) 2005-08-10 CN disclosed
EP-1192196-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-07-13 EP disclosed
EP-1183284-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-04-27 EP disclosed
CN-1168748-C Process for producing polyethylene 伊斯曼化学公司 2004-09-29 CN disclosed
CN-1168752-C Process for making ethylene/olefin interpolymers �Ϻ���ͨ��ѧ 2004-09-29 CN disclosed
CN-1158315-C Process for producing ethylene/olefin interpolymers 伊斯曼化学公司 2004-07-21 CN disclosed
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
EP-1187857-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2004-01-21 EP disclosed
US-6677410-B2 COORDINATION CATALYSTS EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
EP-1187857-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2002-03-20 EP disclosed
EP-1183284-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2002-03-06 EP disclosed
US-20010051587-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-12-13 US disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010029286-A1 Procatalysts, catalyst systems, and use in OLEFIN polymerization EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE 2001-10-11 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
US-6271321-B1 CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY 2001-08-07 US disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed