Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242408 | 0.90 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL10742903 | 0.89 | POLB (0.41) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL9668245 | 0.87 | USP2 (0.42) | PARK7ALDH1A1TSHRKDM4EGAA | |
| SCHEMBL10732971 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAPOLBHPGD | |
| SCHEMBL7234484 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL7236050 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL9667758 | 0.76 | USP2 (0.43) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL9666290 | 0.75 | USP2 (0.42) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL9667449 | 0.74 | MEN1 (0.46) | ALDH1A1TSHRKDM4EGAAUSP2 | |
| SCHEMBL9666432 | 0.73 | DRD2 (0.42) | PARK7ALDH1A1GAAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686224-A | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |