Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242408 | 0.91 | ALDH1A1 (0.43) | POLBALDH1A1LMNAKDM4EGAA | |
| SCHEMBL10745385 | 0.89 | PARK7 (0.40) | POLBALDH1A1LMNAKDM4EGAA | |
| SCHEMBL9667758 | 0.87 | USP2 (0.43) | POLBALDH1A1LMNASRD5A2KDM4E | |
| SCHEMBL7234484 | 0.84 | ALDH1A1 (0.45) | POLBALDH1A1KDM4EGAATSHR | |
| SCHEMBL7236050 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EGAATSHR | |
| SCHEMBL7236923 | 0.78 | ALDH1A1 (0.40) | POLBALDH1A1LMNASRD5A2KDM4E | |
| SCHEMBL9668245 | 0.76 | USP2 (0.42) | ALDH1A1LMNAKDM4EGAATSHR | |
| SCHEMBL9666290 | 0.76 | USP2 (0.42) | POLBALDH1A1LMNAKDM4EGAA | |
| SCHEMBL9667378 | 0.71 | CASP3 (0.48) | POLBALDH1A1KDM4EGAATSHR | |
| SCHEMBL9667216 | 0.71 | KMT2A (0.46) | ALDH1A1LMNASRD5A2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686224-A | Oxindole antiinflammatory agents | PFIZER INC. (US) | 1987-08-11 | — | — | US | disclosed |