Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811050 | 0.90 | EGLN1 (0.43) | EGLN1ALKBH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11018085 | 0.86 | RXRA (0.41) | EGLN1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10816686 | 0.86 | L3MBTL1 (0.43) | EGLN1ALKBH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10813796 | 0.83 | RAB9A (0.46) | EGLN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11021894 | 0.83 | ALKBH1 (0.41) | ALKBH1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL10816545 | 0.78 | EGLN1 (0.41) | EGLN1ALKBH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10814782 | 0.78 | EGLN1 (0.41) | EGLN1ALKBH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11037277 | 0.77 | EGLN1 (0.44) | EGLN1HPGDNPBWR1RXRAGRIN1 | |
| SCHEMBL10745802 | 0.77 | DAO (0.35) | NOTUMNPC1RAB9ATYRHSD17B10 | |
| SCHEMBL10815000 | 0.76 | RXRA (0.46) | EGLN1ALKBH1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087326-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYCOMED AS (NO) | 1987-05-13 | — | — | EP | disclosed |
| US-4539324-A | ANTICANCER AGENTS | NYEGAARD & CO. A/S (NO) | 1985-09-03 | — | — | US | disclosed |
| EP-0087326-A1 | Substituted pyrimidin-2-ones and the salts thereof | NYCOMED AS (NO) | 1983-08-31 | — | — | EP | disclosed |