Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783415 | 0.90 | LMNA (0.48) | KMT2AMEN1HSD17B10LMNATDP1 | |
| SCHEMBL10750973 | 0.83 | KMT2A (0.48) | KMT2AMEN1HSD17B10LMNATDP1 | |
| SCHEMBL10781647 | 0.82 | L3MBTL1 (0.43) | KMT2AMEN1HSD17B10LMNAALDH1A1 | |
| SCHEMBL9632300 | 0.82 | ALDH1A1 (0.54) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL10752136 | 0.80 | SMN1; SMN2 (0.50) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL15787356 | 0.80 | KMT2A (0.47) | KMT2AMEN1HSD17B10LMNATDP1 | |
| SCHEMBL10753056 | 0.80 | GRIN1 (0.40) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL10751967 | 0.78 | LMNA (0.47) | LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25123337 | 0.78 | KMT2A (0.43) | KMT2AMEN1HSD17B10LMNATDP1 | |
| SCHEMBL10748524 | 0.78 | ALOX5 (0.45) | KMT2AMEN1HSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| US-4647579-A | Circulation active novel substituted 4-hydroxy-benzopyrans | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |