Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274621 | 0.84 | POLB (0.52) | POLBSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL874504 | 0.82 | ALOX5 (0.42) | BCL2BCL2L1ALOX5CYP3A4 | |
| SCHEMBL10748552 | 0.81 | CA2 (0.39) | POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL11231888 | 0.78 | TRPV1 (0.37) | ALOX5 | |
| SCHEMBL4486140 | 0.77 | MAPT (0.40) | POLBSMN1; SMN2 | |
| SCHEMBL7948311 | 0.77 | HNF4A (0.50) | SMN1; SMN2HPGD | |
| SCHEMBL7948327 | 0.77 | CA1 (0.53) | LTA4HPOLBSMN1; SMN2IDH1 | |
| SCHEMBL873591 | 0.75 | CA1 (0.40) | ALOX5LTA4HSMN1; SMN2IDH1 | |
| SCHEMBL6300999 | 0.74 | HSP90AA1 (0.50) | LTA4HMEN1HPGDKMT2A | |
| SCHEMBL29044998 | 0.74 | POLB (0.49) | LTA4HPOLBSMN1; SMN2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6261814-B1 | MIXING PURIFIED, BIOLOGICALLY-DERIVED REDUCTASE FROM NOCARDIA SPECIES WITH CARBOXYLIC ACID OR DERIVATIVE; PRODUCTION OF VANILLIN FROM VANILLIC ACID | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-07-17 | — | — | US | disclosed |
| WO-1998040472-A2 | CARBOXYLIC ACID REDUCTASE, AND METHODS OF USING SAME | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5795759-A | Carboxylic acid reductase, and methods of using same | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-08-18 | — | — | US | disclosed |