Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 5/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.46 |
| ▸ | CCR6 | P51684 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751474 | 0.76 | MAPT (0.64) | LMNAMAPTALDH1A1NPSR1HPGD | |
| SCHEMBL11058268 | 0.72 | FGFR1 (0.58) | LMNAMAPTALDH1A1NPSR1HKDC1 | |
| SCHEMBL2268427 | 0.72 | MAPT (0.61) | LMNAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL8657075 | 0.71 | KEAP1 (0.55) | LMNAMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL9368613 | 0.71 | ALDH1A1 (0.55) | LMNAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10446166 | 0.70 | IDO1 (0.52) | LMNAMAPTALDH1A1NPSR1HPGD | |
| SCHEMBL17051223 | 0.69 | ALDH1A1 (0.53) | LMNAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL36533 | 0.68 | ALDH1A1 (0.67) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL27903095 | 0.67 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4ETDP1TP53 | |
| SCHEMBL15827661 | 0.67 | NPSR1 (0.56) | LMNAMAPTALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463142-A | Photocrosslinkable polymers with side groups derived from indenone and the preparation and use of these polymers | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4399259-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; KETONE RESINS; BROMO- AND CHLOROPOLYMERS; PHOTORESISTS | CIBA-GEIGY CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4323701-A | FROM DIHALOGENOMALEIC ANHYDRIDES OR ACYL HALIDE AND AN AROMATIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |