Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973105 | 0.85 | POLB (0.49) | KMT2AMEN1LMNAPOLBTP53 | |
| SCHEMBL10752287 | 0.80 | MEN1 (0.44) | KMT2AMEN1LMNAPOLBTP53 | |
| SCHEMBL8319764 | 0.80 | POLB (0.58) | KMT2AMEN1LMNAPOLBTP53 | |
| SCHEMBL10757418 | 0.79 | LMNA (0.39) | KMT2AMEN1LMNAPOLBRAB9A | |
| SCHEMBL10753215 | 0.75 | ALDH1A1 (0.47) | KMT2ALMNAPOLBALDH1A1GAA | |
| SCHEMBL23039956 | 0.74 | MEN1 (0.48) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL23039954 | 0.74 | MEN1 (0.48) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL13733686 | 0.74 | MEN1 (0.48) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL23058774 | 0.74 | MEN1 (0.48) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL592715 | 0.73 | POLB (0.66) | KMT2AMEN1POLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |