Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752283 | 0.85 | KMT2A (0.48) | POLBMEN1KMT2ATP53MAPT | |
| SCHEMBL10972160 | 0.78 | MEN1 (0.46) | POLBMEN1KMT2AMAOANPC1 | |
| SCHEMBL10973108 | 0.77 | POLB (0.48) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL7217491 | 0.75 | POLB (0.57) | POLBMEN1KMT2ATP53MAPT | |
| SCHEMBL10752178 | 0.74 | LMNA (0.47) | POLBMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL16942604 | 0.74 | POLB (0.62) | POLBMEN1KMT2ATP53MAPT | |
| SCHEMBL23917849 | 0.74 | ALDH1A1 (0.69) | POLBMEN1KMT2ATP53MAPT | |
| SCHEMBL4836408 | 0.74 | ENPP2 (0.71) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL592715 | 0.74 | POLB (0.66) | POLBMEN1KMT2ATP53MAPT | |
| SCHEMBL10598558 | 0.73 | POLB (0.69) | POLBMEN1KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |