Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973108 | 0.85 | POLB (0.48) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL10752283 | 0.80 | KMT2A (0.48) | MEN1LMNAKMT2APOLBTP53 | |
| SCHEMBL10752292 | 0.79 | HDAC6 (0.37) | LMNA | |
| SCHEMBL10757422 | 0.79 | ITGB3 (0.37) | MEN1LMNAKMT2AMAPT | |
| SCHEMBL8319764 | 0.78 | POLB (0.58) | MEN1LMNAKMT2APOLBTP53 | |
| SCHEMBL10753221 | 0.75 | ALDH1A1 (0.48) | MEN1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10749977 | 0.75 | MC4R (0.44) | LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9315961 | 0.73 | POLB (0.61) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL592715 | 0.72 | POLB (0.66) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL590420 | 0.70 | POLB (0.62) | MEN1KMT2APOLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |