Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752178 | 0.82 | LMNA (0.47) | ALDH1A1LMNAPKMKMT2ATBXAS1 | |
| SCHEMBL10757418 | 0.79 | LMNA (0.39) | ALDH1A1LMNAKMT2ACYP3A4KDM4E | |
| SCHEMBL10753221 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAPKMKMT2ARIPK1 | |
| SCHEMBL10752283 | 0.75 | KMT2A (0.48) | ALDH1A1LMNAKMT2AGAAPOLB | |
| SCHEMBL4477889 | 0.73 | TBXAS1 (0.52) | ALDH1A1LMNAPKMKMT2ATBXAS1 | |
| SCHEMBL23039954 | 0.73 | MEN1 (0.48) | ALDH1A1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL13733686 | 0.73 | MEN1 (0.48) | ALDH1A1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL23039956 | 0.73 | MEN1 (0.48) | ALDH1A1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL23058774 | 0.73 | MEN1 (0.48) | ALDH1A1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL10756615 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2ARIPK1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |