Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692929 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL693447 | 0.78 | CNR1 (0.31) | CNR2CNR1 | |
| SCHEMBL692918 | 0.76 | CYP1A2 (0.37) | ALDH1A1 | |
| SCHEMBL1074024 | 0.75 | PDE4A (0.32) | HSD17B10 | |
| SCHEMBL692560 | 0.75 | MPO (0.40) | — | |
| SCHEMBL1073616 | 0.73 | — | — | |
| SCHEMBL692697 | 0.73 | ILK (0.30) | — | |
| SCHEMBL725352 | 0.72 | MPO (0.40) | ALDH1A1 | |
| SCHEMBL1075846 | 0.71 | MPO (0.43) | — | |
| SCHEMBL1074948 | 0.69 | PDE1A (0.31) | KDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | claimed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | claimed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | claimed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | claimed |
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | KRT18, TUBB3, PPOX | SIGMAR1 4278/4885BCHE 2388/4885CNR2 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.