Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45044 | 1.00 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL444337 | 0.86 | CES1 (0.44) | CES2CES1TSHRALDH1A1THRB | |
| SCHEMBL4593133 | 0.86 | CES1 (0.44) | CES2CES1TSHRALDH1A1THRB | |
| Phenol SCHEMBL1415085 | 0.83 | HSD17B3 (0.42) | CES2CES1ALDH1A1TDP1LMNA | |
| Phenol SCHEMBL45542 | 0.83 | HSD17B3 (0.42) | CES2CES1ALDH1A1TDP1LMNA | |
| SCHEMBL27920516 | 0.82 | GPR84 (0.52) | CES2CES1TSHRALDH1A1THRB | |
| SCHEMBL11783133 | 0.79 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL16664 | 0.79 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL671878 | 0.79 | — | — | |
| SCHEMBL2350817 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2777723-B1 | Implantable object comprising selectively degradable copolymers for improved explantability | BIOTRONIK AG (CH) | 2017-12-20 | — | — | EP | claimed |
| EP-2136851-B1 | A COATING OF FAST ABSORPTION OR DISSOLUTION | ABBOTT CARDIOVASCULAR SYSTEMS INC (US) | 2017-09-06 | — | — | EP | claimed |
| US-20140079742-A1 | COATING OF FAST ABSORPTION OR DISSOLUTION | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-03-20 | — | — | US | claimed |
| US-20140074224-A1 | COATING OF FAST ABSORPTION OR DISSOLUTION | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-03-13 | — | — | US | claimed |
| EP-2136851-A2 | A COATING OF FAST ABSORPTION OR DISSOLUTION | Abbott Cardiovascular Systems, Inc. (US) | 2009-12-30 | — | — | EP | claimed |
| WO-2008076731-A2 | A COATING OF FAST ABSORPTION OR DISSOLUTION | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080145393-A1 | Coating of fast absorption or dissolution | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2008-06-19 | — | — | US | claimed |
| WO-1993023570-A1 | OLIGONUCLEOTIDES HAVING CONJUGATES ATTACHED AT THE 2'-POSITION OF THE SUGAR MOIETY | PHARMAGENICS, INC. (US) | 1993-11-25 | — | — | WO | claimed |
| CN-117396497-A | Use of long acting growth hormone for the treatment of inflammation induced diseases | 阿森迪斯药物股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-109843295-B | Combination therapy with controlled release of CNP agonist | 阿森迪斯药物生长障碍股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-107405409-B | CNP prodrugs | 阿森迪斯药物生长障碍股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-3873904-A1 | TETRAHYDROPYRAN (THP)-SUBSTITUTED BICYCLIC-PYRIMIDINEDIONE COMPOUNDS | MyoKardia, Inc. (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3755311-A2 | INDANE-AMINES AS PD-L1 ANTAGONISTS | ChemoCentryx, Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| WO-2020168172-A1 | CONJUGATE COMPOUNDS FOR THE DEGRADATION OF RAF | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-08-20 | — | — | WO | disclosed |
| US-5607659-A | Directed biodistribution of radiolabelled biotin using carbohydrate polymers | NEORX CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| WO-1996033199-A1 | PROCESS FOR MAKING 1-HYDROXYBISPHOSPHONATES | MERCK & CO., INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0683676-A1 | DIRECTED BIODISTRIBUTION OF SMALL MOLECULES | NEORX CORPORATION (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0646019-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-04-05 | — | — | EP | disclosed |
| WO-1994017829-A1 | DIRECTED BIODISTRIBUTION OF SMALL MOLECULES | NEORX CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |
| WO-1993025240-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145393-A1 | Coating of fast absorption or dissolution | TNNC1, SLC10A2, SI | HDAC3 2596/4885HDAC1 1567/4885HDAC2 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.