Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB2 | P47870 | 4/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.65 |
| ▸ | ALB | P02768 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TSPO | P30536 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761287 | 0.92 | GABRA1 (0.74) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL8150 | 0.90 | GABRA2 (0.70) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL2308850 | 0.89 | GABRA1 (0.66) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL2937741 | 0.87 | GABRB2 (0.64) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL28395142 | 0.84 | GABRA1 (0.61) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL1691376 | 0.84 | ALDH1A1 (0.58) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL3028009 | 0.84 | TSPO (0.69) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL12436585 | 0.83 | GABRA1 (0.60) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL2929147 | 0.83 | GABRB2 (0.73) | GABRB2GABRA2ALBOPRK1KCNH2 | |
| SCHEMBL7233460 | 0.82 | SMN1; SMN2 (0.52) | ALBOPRK1KCNH2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981868-B | Imidazopyridine compound, pharmaceutical composition containing compound, preparation method and application thereof | SUN YAT-SEN UNIVERSITY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110981868-A | Imidazopyridine compound, pharmaceutical composition containing compound, preparation method and application thereof | 中山大学 | 2020-04-10 | — | — | CN | disclosed |
| EP-2586780-B1 | 2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACAD MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2017-03-22 | — | — | EP | disclosed |
| US-8980887-B2 | 2-aryl imidazo[1,2-a]pyridine-3-acetamide derivatives, preparation methods and uses thereof | INSTITUTE OF PHARMACOLOGY (CN) | 2015-03-17 | — | — | US | disclosed |
| US-20130203754-A1 | 2-Aryl Imidazo[1,2-a]Pyridine-3-Acetamide Derivatives, Preparation Methods and Uses Thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2013-08-08 | — | — | US | disclosed |
| EP-2586780-A1 | 2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2013-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203754-A1 | 2-Aryl Imidazo[1,2-a]Pyridine-3-Acetamide Derivatives, Preparation Methods and Uses Thereof | TSPO, SLC6A1, TBXA2R | GABRB2 41/4885GABRA2 9/4885ALB 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.