Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.63 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | DHFR | P00374 | 1/20 | 0.61 |
| ▸ | HNF4A | P41235 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DHODH | Q02127 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | GALK1 | P51570 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | PLEC | Q15149 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805528 | 0.95 | SIRT6 (0.65) | SIRT6KMT2APKMDEGS1ACMSD | |
| SCHEMBL1129948 | 0.91 | KMT2A (0.77) | SIRT6KMT2APKMPTPN1ALOX15 | |
| SCHEMBL3296397 | 0.88 | KMT2A (0.83) | SIRT6KMT2APKMDEGS1ACMSD | |
| SCHEMBL7706007 | 0.86 | TOP1 (0.62) | SIRT6KMT2APKMDEGS1ACMSD | |
| SCHEMBL10759208 | 0.84 | MITF (0.64) | SIRT6KMT2APKMPTPN1ALOX15 | |
| SCHEMBL13805546 | 0.83 | SIRT6 (0.53) | SIRT6KMT2APKMMCL1PTPN1 | |
| SCHEMBL3661071 | 0.83 | DEGS1 (0.65) | SIRT6KMT2APKMDEGS1ACMSD | |
| SCHEMBL23226872 | 0.82 | DEGS1 (0.63) | KMT2ADEGS1PTPN1ALOX15MAPT | |
| SCHEMBL23226585 | 0.82 | KMT2A (0.64) | KMT2ADEGS1PTPN1MAPTMEN1 | |
| SCHEMBL10763914 | 0.81 | KMT2A (0.69) | KMT2APKMALOX15MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236329-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITAL-FARMACO S.p.A. (IT) | 1987-09-16 | — | — | EP | claimed |
| WO-1986003199-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITALFARMACO S.P.A. (IT) | 1986-06-05 | — | — | WO | claimed |
| EP-0236329-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITAL-FARMACO S.p.A. (IT) | 1987-09-16 | — | — | EP | disclosed |
| CN-85109554-A | The preparation method of aminosallcylic acid derivative and salt thereof and its medicinal compositions | — | 1986-07-23 | — | — | CN | disclosed |
| WO-1986003199-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITALFARMACO S.P.A. (IT) | 1986-06-05 | — | — | WO | disclosed |