Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805528 | 0.87 | SIRT6 (0.65) | SIRT6TDP1MCL1KMT2AMEN1 | |
| SCHEMBL10758235 | 0.83 | SIRT6 (0.64) | SIRT6TDP1GALK1CASP6MCL1 | |
| SCHEMBL7706007 | 0.79 | TOP1 (0.62) | SIRT6TDP1MCL1KMT2AMEN1 | |
| SCHEMBL7030719 | 0.77 | KMT2A (0.60) | TDP1MCL1KMT2AMEN1MAPT | |
| SCHEMBL1129948 | 0.77 | KMT2A (0.77) | SIRT6TDP1KMT2AMEN1MAPT | |
| SCHEMBL10759208 | 0.76 | MITF (0.64) | SIRT6TDP1KMT2AMEN1MAPT | |
| SCHEMBL31376926 | 0.76 | SIRT6 (0.62) | SIRT6TDP1KMT2AMEN1MAPT | |
| SCHEMBL9150565 | 0.75 | KDM4E (0.71) | SIRT6TDP1KMT2AMEN1MAPT | |
| SCHEMBL9150180 | 0.74 | ALDH1A1 (0.84) | MCL1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL14184959 | 0.74 | MAPK1 (0.58) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162280-A1 | DETECTING SOLUBLE A-BETA | GENERAL ELECTRIC COMPANY (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162280-A1 | DETECTING SOLUBLE A-BETA | F13B, FGB, IL1A | SIRT6 4055/4885TDP1 3070/4885GALK1 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.