Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762105 | 1.00 | KMT2A (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10757702 | 0.84 | KMT2A (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10757707 | 0.84 | KMT2A (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10753480 | 0.76 | TSHR (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10753482 | 0.76 | TSHR (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10755749 | 0.76 | MAPT (0.53) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10755753 | 0.76 | MAPT (0.53) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10754644 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10754642 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10759322 | 0.70 | GSK3B (0.36) | KMT2AMEN1MAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |