Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AOC2 | O75106 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525414 | 0.82 | HTT (0.40) | GAAALDH1A1HTTPKM | |
| SCHEMBL29098238 | 0.82 | THRB (0.39) | GAAALDH1A1HTTTHRBSMN1; SMN2 | |
| SCHEMBL163578 | 0.81 | ALDH1A1 (0.50) | GAAALDH1A1HTTTHRBSMN1; SMN2 | |
| SCHEMBL3156584 | 0.81 | ALDH1A1 (0.39) | GAAALDH1A1HTTTHRBSMN1; SMN2 | |
| Bicarbonate SCHEMBL27510048 | 0.79 | ALDH1A1 (0.49) | GAAALDH1A1HTTTHRBSMN1; SMN2 | |
| SCHEMBL2788102 | 0.79 | ALDH1A1 (0.49) | GAAALDH1A1HTTTHRBSMN1; SMN2 | |
| SCHEMBL11882498 | 0.79 | KDM4E (0.43) | ALDH1A1HTTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL6288493 | 0.79 | ALOX15 (0.42) | ALDH1A1THRBCYP2C19MEN1KMT2A | |
| SCHEMBL10388997 | 0.78 | ALOX15 (0.45) | SMN1; SMN2KDM4EAOC2MAOAMAOB | |
| SCHEMBL27943095 | 0.77 | AOC2 (0.36) | GAAALDH1A1THRBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519715-B1 | NANOPARTICULATE FIBRATE FORMULATIONS | ALKERMES PHARMA IRELAND LTD (IE) | 2023-02-22 | — | — | EP | disclosed |
| US-20110305733-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING METFORMIN AND A FIBRATE, AND PROCESSES FOR OBTAINING THEM | FOURNIER LABORATORIES IRELAND LIMITED (IE) | 2011-12-15 | — | — | US | disclosed |
| EP-1706102-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING METFORMIN AND A FIBRATE, AND PROCESSES FOR OBTAINING THEM | FOURNIER LAB IRELAND LTD (IE) | 2011-08-24 | — | — | EP | disclosed |
| US-7931917-B2 | Phospholipid-free, having a D50 particle size of less than 500 nm, and having a surface stabilizer; improved pharmacokinetic profiles and reduced fed/fasted variability | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2011-04-26 | — | — | US | disclosed |
| US-7927627-B2 | Particles of a fibrate having a particle size of less than 2000 nm, hypromellose, dioctyl sodium sulfosuccinate, and sodium lauryl sulfate as surface stabilizers | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2011-04-19 | — | — | US | disclosed |
| EP-2271316-A2 | FENOFIBRATE DOSAGE FORMS | Elan Pharma International Limited (IE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009120919-A2 | FENOFIBRATE DOSAGE FORMS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2009-10-01 | — | — | WO | disclosed |
| US-20080241070-A1 | FENOFIBRATE DOSAGE FORMS | ELAN PHARMA INTERNATIONAL LTD. | 2008-10-02 | — | — | US | disclosed |
| US-20080138424-A1 | Nanoparticulate fibrate formulations | Elan Pharma Internationa, Ltd. | 2008-06-12 | — | — | US | disclosed |
| US-20080095851-A1 | Nanoparticulate fibrate formulations | ELAN PHARMA INTERNATIONAL, LTD. | 2008-04-24 | — | — | US | disclosed |
| WO-2004041250-A2 | NANOPARTICULATE FIBRATE FORMULATIONS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087656-A1 | Nanoparticulate fibrate formulations | ELAN PHARMA INTERNATIONAL, LTD. | 2004-05-06 | — | — | US | disclosed |
| EP-0585366-B1 | USING ALLOSTERIC HEMOGLOBIN MODIFIERS TO DECREASE OXYGEN AFFINITY IN BLOOD | UNIV VIRGINIA COMMONWEALTH (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20040058009-A1 | Nanoparticulate fibrate formulations | ELAN PHARMA INTERNATIONAL, LTD. | 2004-03-25 | — | — | US | disclosed |
| US-20030224058-A1 | Fibrate particles of an effective average particle size of less than 2000 nm. having a stabilizer associated with the surface; improved pharmacokinetic profiles and reduced fed/fasted variability. | ELAN PHARMA INTERNATIONAL, LTD. | 2003-12-04 | — | — | US | disclosed |
| EP-0479470-B1 | Corrosion-inhibited antifreeze/coolant composition | TEXACO CHEMICAL (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5177106-A | 4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| US-4025515-A | HERBICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | disclosed |
| US-3907792-A | Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof | MIEVILLE ANDRE | 1975-09-23 | — | — | US | disclosed |
| US-3907792-A | Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof | MIEVILLE ANDRE | 1975-09-23 | — | — | US | disclosed |