Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765095 | 0.88 | PDE3B (0.33) | PDE3BPDE3APBRM1 | |
| SCHEMBL10761515 | 0.84 | PDE3B (0.38) | PDE3BPDE3AALDH1A1GAAMAPT | |
| SCHEMBL10760273 | 0.83 | PDE3B (0.42) | PDE3BPDE3AALDH1A1PBRM1 | |
| SCHEMBL10765719 | 0.83 | PDE3A (0.38) | PDE3BPDE3AGAAMAPT | |
| SCHEMBL10763897 | 0.83 | PDE3A (0.40) | PDE3BPDE3AMAPT | |
| SCHEMBL10765553 | 0.81 | PTGS2 (0.37) | PDE3BPDE3APBRM1TNNC1 | |
| SCHEMBL10761023 | 0.81 | MAOB (0.44) | PDE3BPDE3AALDH1A1GAAMAPT | |
| SCHEMBL10762059 | 0.80 | PDE3B (0.41) | PDE3BPDE3AALDH1A1PBRM1TNNC1 | |
| SCHEMBL10765802 | 0.79 | PDE3B (0.55) | PDE3BPDE3ACA12CA1CA2 | |
| SCHEMBL10763441 | 0.76 | KDM4E (0.45) | PDE3BPDE3AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |