Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075776 | 0.86 | MAPT (0.40) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL698892 | 0.83 | BCAT1 (0.53) | MAPTALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL1074412 | 0.83 | NPC1 (0.56) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL1075654 | 0.83 | MAPT (0.39) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18218823 | 0.78 | MAPT (0.68) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL16486063 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL1074593 | 0.74 | RAB9A (0.45) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL13741146 | 0.73 | GAA (0.54) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL28724626 | 0.73 | MAPT (0.43) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL693500 | 0.71 | RAB9A (0.42) | MAPTALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | claimed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | claimed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | claimed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | claimed |
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | KRT18, TUBB3, PPOX | MAPT 354/4885ALDH1A1 510/4885LMNA 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.