Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831903 | 0.88 | FFAR1 (0.46) | MMP9PTGS2FFAR1SMN1; SMN2 | |
| SCHEMBL11837111 | 0.85 | MMP2 (0.45) | MMP2MMP9PTGS2FFAR1KMT2A | |
| SCHEMBL11829934 | 0.76 | MMP2 (0.50) | MMP2MMP9PTGS2FFAR1KMT2A | |
| SCHEMBL11829237 | 0.76 | FFAR1 (0.44) | MMP2MMP9PTGS2FFAR1CHRNB2 | |
| SCHEMBL6397691 | 0.75 | SLC6A3 (0.42) | MMP2MMP9KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10158 | 0.75 | MMP9 (0.52) | MMP2MMP9PTGS2FFAR1 | |
| SCHEMBL11832271 | 0.74 | FFAR1 (0.41) | MMP2MMP9PTGS2FFAR1CHRNB2 | |
| SCHEMBL11825640 | 0.73 | FFAR1 (0.44) | MMP9PTGS2FFAR1SMN1; SMN2 | |
| SCHEMBL11829227 | 0.71 | PTGS2 (0.45) | MMP9PTGS2FFAR1SMN1; SMN2 | |
| Biphenyl SCHEMBL8982412 | 0.70 | KMT2A (0.70) | MMP2MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |