Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.45 |
| ▸ | CA9 | Q16790 | 9/20 | 0.45 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA6 | P23280 | 5/20 | 0.45 |
| ▸ | CA5A | P35218 | 5/20 | 0.45 |
| ▸ | CA7 | P43166 | 5/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665121 | 0.83 | CA2 (0.47) | CA1CA2CA9CA12CA6 | |
| SCHEMBL233320 | 0.76 | LMNA (0.61) | CA1CA2CA9CA12CA6 | |
| SCHEMBL29365636 | 0.76 | LMNA (0.61) | CA1CA2CA9CA12CA6 | |
| SCHEMBL23536145 | 0.72 | PDIA6 (0.53) | CA1CA2CA9CA12CA6 | |
| SCHEMBL6669968 | 0.72 | CA2 (0.55) | CA1CA2CA9CA12CA6 | |
| SCHEMBL1925948 | 0.72 | CA2 (0.52) | CA1CA2CA9CA12CA6 | |
| SCHEMBL1368195 | 0.72 | CA2 (0.61) | CA1CA2CA9CA12CA6 | |
| SCHEMBL588896 | 0.72 | CA2 (0.61) | CA1CA2CA9CA12CA6 | |
| SCHEMBL11374683 | 0.72 | CA2 (0.47) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2011324 | 0.71 | CA2 (0.62) | CA1CA2CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652531-A | Fluorescent protein binding assays with unsymmetrical fluorescein derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-03-24 | — | — | US | disclosed |
| US-4439356-A | XANTHENES, IMMUNOASSAY | SYVA COMPANY (US) | 1984-03-27 | — | — | US | disclosed |