SCHEMBL3665121

SCHEMBL3665121

Cc1ccc(S(N)(=O)=O)cc1N=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.47
CA1 P00915 9/20 0.47
CA9 Q16790 9/20 0.47
CA12 O43570 8/20 0.47
CA6 P23280 3/20 0.47
CA5A P35218 3/20 0.47
CA7 P43166 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
CA3 P07451 1/20 0.47
POLB P06746 2/20 0.43
HTT P42858 1/20 0.43
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
CA4 P22748 2/20 0.41
CA14 Q9ULX7 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 2/20 0.41
PKM P14618 2/20 0.41
SOS1 Q07889 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10770107 0.83 CA1 (0.45) CA2CA1CA9CA12CA6
SCHEMBL27903840 0.82 PTGS2 (0.40) PTGS2LMNA
SCHEMBL6851838 0.81 ALDH1A1 (0.40) CA2CA1CA12CA7POLB
SCHEMBL14028112 0.78 CA2 (0.57) CA2CA1CA9CA12CA6
SCHEMBL29230354 0.78 LMNA (0.61) CA2CA1CA9CA12CA6
SCHEMBL233320 0.77 LMNA (0.61) CA2CA1CA9CA12CA6
SCHEMBL29365636 0.77 LMNA (0.61) CA2CA1CA9CA12CA6
SCHEMBL14028113 0.77 CA2 (0.53) CA2CA1CA9CA12CA6
SCHEMBL11374683 0.77 CA2 (0.47) CA2CA1CA9CA12CA6
SCHEMBL12510202 0.74 LMNA (0.50) POLBLMNAMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4295150-A1 METHODS AND COMPOSITIONS FOR DIAGNOSING, GERMLINE MISMATCH REPAIR DEFICIENCIES, LYNCH SYNDROME AND ASSESSING GERMLINE RISKS OF CANCER Morgan and Mendel Genomics, Inc. (US) 2023-12-27 EP disclosed
EP-3941920-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2022-01-26 EP disclosed
WO-2018029711-A2 PROCESS FOR THE PREPARATION OF VENETOCLAX MYLAN LABORATORIES LIMITED (IN) 2018-02-15 WO disclosed
EP-2237788-A2 AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF Aires Pharmaceuticals, Inc. (US) 2010-10-13 EP disclosed
WO-2009086470-A2 AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF AIRES PHARMACEUTICALS, INC. (US) 2009-07-09 WO disclosed
EP-1648924-A2 DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME The Nottingham Trent University (GB) 2006-04-26 EP disclosed
WO-2004113363-A2 DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME THE NOTTINGHAM TRENT UNIVERSITY (GB) 2004-12-29 WO disclosed
WO-1998029115-A1 TRANSITION-METAL NITROSYL COMPOUNDS AS SMOOTH MUSCLE RELAXANTS UNIVERSITY OF BRITISH COLUMBIA (CA) 1998-07-09 WO disclosed
EP-0824539-A1 DIALKYLTIACUMICIN COMPOUNDS Abbott Laboratories (US) 1998-02-25 EP disclosed
WO-1996035702-A1 DIALKYLTIACUMICIN COMPOUNDS ABBOTT LABORATORIES (US) 1996-11-14 WO disclosed
EP-0731841-A1 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS Cangene Corporation (CA) 1996-09-18 EP disclosed
WO-1995017512-A2 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS CANGENE CORPORATION (CA) 1995-06-29 WO disclosed
US-5356999-A Contains an ethylene-propylene copolymer which has been grafted with an unsaturated reactive monomer and thereafter with amines containing sulfonamide units; lubricating oil additive TEXACO INC. (US) 1994-10-18 US disclosed
WO-1994007485-A1 ZARAGOZIC ACID DERIVATIVES AND METHODS OF TREATING HYPERCHOLESTEROLEMIA, FUNGAL GROWTH, AND CANCER THEREWITH MERCK & CO., INC. (US) 1994-04-14 WO disclosed
EP-0366059-A2 Carbocyclic nucleoside analogs BRISTOL-MYERS SQUIBB COMPANY (US) 1990-05-02 EP disclosed
EP-0257940-A2 A method of analyzing high molecular weight dispersants in motor oils The Lubrizol Corporation (US) 1988-03-02 EP disclosed