Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139164 | 0.81 | MEN1 (0.54) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL10558423 | 0.79 | SMN1; SMN2 (0.56) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL8808020 | 0.78 | ADRA2A (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL19484420 | 0.75 | MMP1 (0.40) | SMN1; SMN2LMNAALDH1A1HTTTSHR | |
| SCHEMBL10620953 | 0.74 | LTA4H (0.57) | ALDH1A1HTTTSHRCYP3A4HSD17B10 | |
| SCHEMBL28840343 | 0.74 | MEN1 (0.65) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL667594 | 0.73 | MEN1 (0.64) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL6943230 | 0.72 | MEN1 (0.63) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL1748538 | 0.72 | MEN1 (0.63) | MEN1KMT2AAPAF1SMN1; SMN2LMNA | |
| SCHEMBL22010907 | 0.72 | MEN1 (0.63) | MEN1KMT2AAPAF1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243868-A2 | Pyridylthio-acylanilides | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |