Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | FURIN | P09958 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620953 | 0.90 | LTA4H (0.57) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL11291286 | 0.88 | ALDH1A1 (0.64) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL19484420 | 0.86 | MMP1 (0.40) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL14493735 | 0.84 | CYP3A4 (0.47) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL12669932 | 0.84 | PARP10 (0.52) | ADRA2AADRA2BADRA2CALDH1A1HSD17B10 | |
| SCHEMBL14509945 | 0.82 | ALDH1A1 (0.47) | ADRA2AADRA2BADRA2CALDH1A1TSHR | |
| SCHEMBL234461 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10TP53MAPK1 | |
| SCHEMBL20334904 | 0.78 | HTT (0.59) | ALDH1A1TSHRHSD17B10CYP3A4TDP1 | |
| SCHEMBL156005 | 0.78 | CA1 (0.58) | ALDH1A1TSHRHSD17B10TP53MAPK1 | |
| SCHEMBL10770236 | 0.78 | MEN1 (0.57) | ALDH1A1TSHRHSD17B10CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619374-B1 | Colorimetric determination of an analyte using benzyl alcohol dehydrogenase and a chromogenic redox-indicator | BOEHRINGER MANNHEIM GMBH (DE) | 1997-08-13 | — | — | EP | claimed |
| US-5445943-A | Reduction of an aromatic nitrosoaniline compound to a colored quinone diimine | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | claimed |
| EP-0619374-A2 | Colorimetric determination of an analyte using benzyl alcohol dehydrogenase and a chromogenic redox-indicator | Roche Diagnostics GmbH (DE) | 1994-10-12 | — | — | EP | claimed |