Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26788467 | 0.90 | HRH4 (0.44) | LDHAHRH4F10 | |
| SCHEMBL21186191 | 0.85 | HRH4 (0.50) | LDHAKMT2AMEN1HRH4KDM4E | |
| SCHEMBL7008838 | 0.85 | HRH4 (0.48) | LDHAHRH4F10F2PLAT | |
| SCHEMBL22886364 | 0.85 | LDHA (0.44) | LDHAHRH4F10F2PLAT | |
| Hydrochloric Acid SCHEMBL16684861 | 0.83 | HRH4 (0.47) | LDHAHRH4F10F2PLAT | |
| SCHEMBL20756582 | 0.82 | LDHA (0.42) | LDHAHRH4F10F2PLAT | |
| SCHEMBL803613 | 0.82 | HRH4 (0.56) | LDHAHRH4 | |
| SCHEMBL425041 | 0.82 | HRH4 (0.56) | LDHAALDH1A1KMT2AMEN1HRH4 | |
| SCHEMBL9877120 | 0.81 | ALDH1A1 (0.44) | USP2ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL26156933 | 0.81 | USP2 (0.45) | USP2ALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281873-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281873-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | PORCN, SLC6A1, SLC6A11 | LDHA 3398/4885USP2 4366/4885ALDH1A1 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.