Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962567 | 0.82 | DPP4 (0.40) | KDM4EHPGDMAPTLMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL1092533 | 0.80 | DPP4 (0.39) | KDM4EHPGDMAPTLMNACYP3A4 | |
| Bicarbonate SCHEMBL9177243 | 0.80 | LMNA (0.41) | HPGDLMNATDP1KMT2AL3MBTL1 | |
| SCHEMBL9141560 | 0.76 | MAPT (0.38) | KDM4EHPGDMAPTLMNACYP3A4 | |
| SCHEMBL9144368 | 0.72 | HPGD (0.35) | KDM4EHPGDMAPTLMNACYP3A4 | |
| SCHEMBL7680453 | 0.72 | KDM4E (0.35) | KDM4EHPGDMAPTLMNACYP3A4 | |
| SCHEMBL4635239 | 0.70 | HTR1A (0.38) | KDM4EHPGDLMNAALDH1A1KMT2A | |
| SCHEMBL12770109 | 0.69 | CYP2D6 (0.39) | LMNAALDH1A1KMT2A | |
| SCHEMBL5069672 | 0.67 | HTR1A (0.39) | KDM4EHPGDMAPTLMNAALDH1A1 | |
| SCHEMBL9798045 | 0.67 | HTR1A (0.37) | LMNACYP3A4HSD17B10KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448686-A4 | STABILIZED IMAGEABLE COATING COMPOSITION AND PRINTING PLATE PRECURSOR | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1448686-A1 | STABILIZED IMAGEABLE COATING COMPOSITION AND PRINTING PLATE PRECURSOR | Kodak Polychrome Graphics LLC (US) | 2004-08-25 | — | — | EP | claimed |
| US-6762223-B2 | CARBON PIGMENT DISPERSIBLE IN WATER; POLYMER COMPRISING AT LEAST ONE IONOMERIC POLYMER SUBUNIT; AND AT LEAST ONE HIGH MOLECULAR WEIGHT THICKENING AGENT WHICH SHOWS PSEUDOPLASTIC BEHAVIOR. | KODAK POLYCHROME GRAPHICS LLC | 2004-07-13 | — | — | US | claimed |
| US-20040103801-A1 | System for direct-to-press imaging | KODAK POLYCHROME GRAPHICS, LLC | 2004-06-03 | — | — | US | claimed |
| US-6610458-B2 | Applying coating to printing cylinder which changes affinity for printing fluid upon exposure to radiation; lithography | KODAK POLYCHROME GRAPHICS LLC | 2003-08-26 | — | — | US | claimed |
| US-20030134936-A1 | Carbon pigment dispersible in water; polymer comprising at least one ionomeric polymer subunit; and at least one high molecular weight thickening agent which shows pseudoplastic behavior. | EASTMAN KODAK COMPANY | 2003-07-17 | — | — | US | claimed |
| WO-2003037972-A1 | STABILIZED IMAGEABLE COATING COMPOSITION AND PRINTING PLATE PRECURSOR | KODAK POLYCHROME GRAPHICS LLC (US) | 2003-05-08 | — | — | WO | claimed |
| US-20030056669-A1 | Method and system for direct-to-press imaging | KODAK (NEAR EAST) INC. | 2003-03-27 | — | — | US | claimed |
| WO-2003010600-A2 | METHOD AND SYSTEM FOR DIRECT-TO-PRESS IMAGING | KODAK POLYCHROME GRAPHICS LLC (US) | 2003-02-06 | — | — | WO | claimed |
| US-6190830-B1 | UNITS CONTAINING AN ORGANOAMMONIUM, ORGANOPHOSPHONIUM OR ORGANOSULFONIUM GROUP THAT REACTS TO PROVIDE INCREASED OLEOPHILICITY (INK RECEPTIVITY) IN RESPONSE TO HEAT. | KODAK POLYCHROME GRAPHICS LLC | 2001-02-20 | — | — | US | claimed |
| EP-1972439-B1 | On-press developable lithographic printing plate precursor | FUJIFILM CORP (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20080229956-A1 | ON-PRESS DEVELOPABLE LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| EP-1972439-A2 | On-press developable lithographic printing plate precursor | FUJIFILM Corporation (JP) | 2008-09-24 | — | — | EP | disclosed |
| EP-1245383-B1 | Thermal switchable composition and imaging member containing polymethine IR dye and methods of imaging and printing | EASTMAN KODAK CO (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1611213-A1 | INKJET INK COMPOSITION AND INK/RECEIVER COMBINATION | EASTMAN KODAK COMPANY (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1093417-A1 | PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING | Kodak Polychrome Graphics Company Ltd. (US) | 2001-04-25 | — | — | EP | disclosed |
| US-6190830-B1 | UNITS CONTAINING AN ORGANOAMMONIUM, ORGANOPHOSPHONIUM OR ORGANOSULFONIUM GROUP THAT REACTS TO PROVIDE INCREASED OLEOPHILICITY (INK RECEPTIVITY) IN RESPONSE TO HEAT. | KODAK POLYCHROME GRAPHICS LLC | 2001-02-20 | — | — | US | disclosed |
| US-6159657-A | Thermal imaging composition and member containing sulfonated ir dye and methods of imaging and printing | EASTMAN KODAK COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| WO-2000063025-A1 | PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING | KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) | 2000-10-26 | — | — | WO | disclosed |
| EP-0990516-A1 | Processless direct write printing plate and methods of imaging and printing | Kodak Polychrome Graphics LLC (US) | 2000-04-05 | — | — | EP | disclosed |