SCHEMBL8962567

SCHEMBL8962567

C=CC(c1ccccc1)[S+](C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.40
LMNA P02545 4/20 0.36
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 4/20 0.35
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 3/20 0.35
ALOX15 P16050 3/20 0.35
TSHR P16473 3/20 0.35
F2 P00734 1/20 0.35
HPGD P15428 3/20 0.34
USP2 O75604 2/20 0.34
TP53 P04637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALOX12 P18054 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TRPA1 O75762 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1092533 0.98 DPP4 (0.39) DPP4LMNACYP2C19KDM4EMAPT
Bicarbonate SCHEMBL9177243 0.88 LMNA (0.41) LMNACYP2C19HPGDTDP1KMT2A
SCHEMBL1077218 0.82 KDM4E (0.38) LMNAKDM4EMAPTALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL9359182 0.81 KDM4E (0.36) LMNAKDM4EALDH1A1CYP3A4ALOX15
SCHEMBL12770109 0.79 CYP2D6 (0.39) DPP4LMNAALDH1A1TSHRF2
SCHEMBL776592 0.76 CYP2C19 (0.35) DPP4LMNACYP2C19KDM4EMAPT
SCHEMBL9651702 0.71 CYP2C19 (0.40) DPP4CYP2C19KDM4EMAPTALDH1A1
SCHEMBL7808281 0.70 TRPA1 (0.47) DPP4LMNACYP2C19KDM4EALDH1A1
SCHEMBL9719434 0.70 TRPA1 (0.47) DPP4LMNACYP2C19KDM4EALDH1A1
SCHEMBL132606 0.70 TRPA1 (0.47) DPP4LMNACYP2C19KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580650-A CONTACTING POROUS SUPPORT WITH POLYMER SOLUTION, IRRADIATING THE POLYMER TO FORM FILM, FIXING THE FILM WITH GLUE LAYER TO SUPPORT THE DOW CHEMICAL COMPANY (US) 1996-12-03 US claimed
US-4877551-A Aqueous suspension of delaminated vermiculite HERCULES INCORPORATED (US) 1989-10-31 US claimed
JP-1130707-A None JP disclosed
US-5580650-A CONTACTING POROUS SUPPORT WITH POLYMER SOLUTION, IRRADIATING THE POLYMER TO FORM FILM, FIXING THE FILM WITH GLUE LAYER TO SUPPORT THE DOW CHEMICAL COMPANY (US) 1996-12-03 US disclosed
EP-0695437-A1 PHOTOCURABLE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1996-02-07 EP disclosed
US-5464538-A Reverse osmosis membrane THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed
WO-1994024609-A2 PHOTOCURABLE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1994-10-27 WO disclosed
US-5310581-A Photoresists, reacting photolabile onium with a photoreactive nucleophile, modified vinylbenzyl chloride polymer THE DOW CHEMICAL COMPANY (US) 1994-05-10 US disclosed
US-5238747-A Compounds with onium groups cured with compound having nucleophilic groups; photoresists release agents THE DOW CHEMICAL COMPANY (US) 1993-08-24 US disclosed
EP-0316525-B1 POLYAMIDE REVERSE OSMOSIS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1992-12-02 EP disclosed
EP-0220660-B1 SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP disclosed
US-4812260-A INTERCALATING ORGANO-CATION SALTS INTO VERMICULITE UNDER SHEARING CONDITIONS HERCULES INCORPORATED (US) 1989-03-14 US disclosed
US-4797187-A COACERVATION OF CATIONS THE DOW CHEMICAL COMPANY (US) 1989-01-10 US disclosed
EP-0282928-A2 Process for production of mineral dispersions HERCULES INCORPORATED (US) 1988-09-21 EP disclosed
EP-0282093-A2 Aqueous suspension of delaminated vermiculite HERCULES INCORPORATED (US) 1988-09-14 EP disclosed
US-4769148-A Novel polyamide reverse osmosis membranes THE DOW CHEMICAL COMPANY (US) 1988-09-06 US disclosed
US-4704324-A REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION THE DOW CHEMICAL COMPANY (US) 1987-11-03 US disclosed
WO-1987002682-A1 SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1987-05-07 WO disclosed
EP-0220660-A2 Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups THE DOW CHEMICAL COMPANY (US) 1987-05-06 EP disclosed
US-4431768-A CATIONIC ADDITION POLYMERS CONTAINING SULFONIUM AND ISOTHIOURONIUM GROUPS THE DOW CHEMICAL COMPANY (US) 1984-02-14 US disclosed