Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928074 | 0.84 | PDPK1 (0.59) | KIF11PDPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL10774096 | 0.82 | PTGS2 (0.54) | KIF11PDPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL658500 | 0.81 | KIF11 (0.69) | KIF11PDPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL31512491 | 0.81 | KIF11 (0.69) | KIF11PDPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL6009670 | 0.80 | KDM4E (0.84) | KIF11KDM4EALDH1A1MEN1HCRTR1 | |
| SCHEMBL147263 | 0.80 | PARP1 (0.73) | KIF11PDPK1KDM4EALDH1A1KMT2A | |
| SCHEMBL29377098 | 0.80 | PARP1 (0.73) | KIF11PDPK1KDM4EALDH1A1KMT2A | |
| SCHEMBL1181911 | 0.78 | HTR7 (0.68) | KIF11PDPK1KDM4EALDH1A1HTR7 | |
| SCHEMBL28435277 | 0.78 | KIF11 (0.64) | KIF11PDPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL30202297 | 0.78 | HTR7 (0.68) | KIF11PDPK1KDM4EALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247222-A1 | Carbazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-12-02 | — | — | EP | disclosed |