Sugi Predict

Sugi Predict / Compounds / SCHEMBL658500

SCHEMBL658500

SCHEMBL658500

CC(=O)c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 5/20 0.69
▸ HTR7 P34969 1/20 0.59
▸ HTR2B P41595 1/20 0.59
▸ KDM4E B2RXH2 3/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ MTNR1A P48039 1/20 0.55
▸ MTNR1B P49286 1/20 0.55
▸ MAOA P21397 1/20 0.55
▸ IMPDH2 P12268 1/20 0.55
▸ ALDH1A1 P00352 3/20 0.54
▸ MAPT P10636 2/20 0.54
▸ HPGD P15428 1/20 0.54
▸ AHR P35869 1/20 0.53
▸ PARP1 P09874 3/20 0.53
▸ PDPK1 O15530 1/20 0.52
▸ MEN1 O00255 1/20 0.51
▸ HCRTR1 O43613 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31512491 1.00 KIF11 (0.69) KIF11HTR7HTR2BKDM4EKMT2A
SCHEMBL13271380 0.92 MAOA (0.67) KIF11HTR7HTR2BKDM4EKMT2A
SCHEMBL6009602 0.91 KIF11 (0.69) KIF11HTR7HTR2BMAOAIMPDH2
SCHEMBL31179919 0.91 KIF11 (0.69) KIF11HTR7HTR2BMAOAIMPDH2
SCHEMBL31244397 0.89 KIF11 (0.69) KIF11KDM4EKMT2AMTNR1AMTNR1B
SCHEMBL2028709 0.89 KIF11 (0.69) KIF11KDM4EKMT2AMTNR1AMTNR1B
SCHEMBL147263 0.84 PARP1 (0.73) KIF11HTR7HTR2BKDM4EKMT2A
SCHEMBL29377098 0.84 PARP1 (0.73) KIF11HTR7HTR2BKDM4EKMT2A
Carbazole SCHEMBL28153769 0.83 ALDH1A1 (0.56) KIF11KDM4EKMT2AMTNR1AMTNR1B
SCHEMBL28435277 0.82 KIF11 (0.64) KIF11HTR7HTR2BKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102140065-B Process for producing diaryl carbonate CHINA PETROCHEMICAL DEV CORP 2013-07-24 — — CN claimed
US-8212066-B2 Process for producing diaryl carbonates CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) 2012-07-03 — — US claimed
CN-102140065-A Process for producing diaryl carbonate CHINA PETROCHEMICAL DEV CORP 2011-08-03 — — CN claimed
US-20110152558-A1 PROCESS FOR PRODUCING DIARYL CARBONATES CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) 2011-06-23 — — US claimed
EP-0151423-A2 Process for the preparation of a carbazole derivative F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-14 — — EP claimed
JP-61140564-A — — None — — JP disclosed
US-10243154-B2 Platinum(II) complexes for OLED applications VERSITECH LIMITED (CN) 2019-03-26 — — US disclosed
US-10243154-B2 Platinum(II) complexes for OLED applications VERSITECH LIMITED (CN) 2019-03-26 — — US disclosed
US-10008681-B2 Platinum(II) complexes for OLED applications VERSITECH LIMITED (CN) 2018-06-26 — — US disclosed
US-10008681-B2 Platinum(II) complexes for OLED applications VERSITECH LIMITED (CN) 2018-06-26 — — US disclosed
US-10008681-B2 Platinum(II) complexes for OLED applications VERSITECH LIMITED (CN) 2018-06-26 — — US disclosed
US-20160181551-A1 PLATINUM(II) COMPLEXES FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (CN) 2016-06-23 — — US disclosed
EP-0151423-A2 Process for the preparation of a carbazole derivative F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-14 — — EP disclosed
EP-0151423-A2 Process for the preparation of a carbazole derivative F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-14 — — EP disclosed
US-4095032-A PHOTOSENSITIVE POLYMERIC MATERIAL AND ELECTROPHOTOMETRIC MATERIAL PREPARED BY REACTING SECONDARY AROMATIC AMINE WITH VINYL ALKYLETHER OR VINYL ACETATE IN THE PRESENCE OF STRONG ACID AND HG (II) OR PB (IV) CATALYST SIROTKINA EKATERINA EGOROVNA 1978-06-13 — — US disclosed
US-4076527-A TREATED VANADYL PHTHALOCYANINE PIGMENT PARTICLES XEROX CORPORATION (US) 1978-02-28 — — US disclosed
US-4038468-A POLY-N-VINYL HETEROCYCLIC AMINES FROM VINYL ETHERS AND SECONDARY AMINES SIROTKINA EKATERINA EGOROVNA 1977-07-26 — — US disclosed
US-4007317-A A POLYVINYL CARBAZOLE SIROTKINA EKATERINA EGOROVNA 1977-02-08 — — US disclosed
US-3986873-A ELECTROGRAPHY SIROTKINA EKATERINA EGOROVNA 1976-10-19 — — US disclosed
US-3978029-A POLYCARBAZOLES XEROX CORPORATION (US) 1976-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243154-B2 Platinum(II) complexes for OLED applications OCIAD2, OCIAD1, PDCD2L KIF11 856/4885HTR7 4335/4885HTR2B 4291/4885
US-20110152558-A1 PROCESS FOR PRODUCING DIARYL CARBONATES CA2, POR, CBR3 KIF11 4130/4885HTR7 2538/4885HTR2B 1997/4885
US-20160181551-A1 PLATINUM(II) COMPLEXES FOR OLED APPLICATIONS OCIAD2, OCIAD1, PDCD2L KIF11 856/4885HTR7 4335/4885HTR2B 4291/4885
US-10008681-B2 Platinum(II) complexes for OLED applications OCIAD2, OCIAD1, PDCD2L KIF11 856/4885HTR7 4335/4885HTR2B 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.