SCHEMBL1077286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18236377	0.92	—	—
	SCHEMBL31142144	0.80	HSD11B1 (0.33)	MAPK1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL24330730	0.77	MEN1 (0.33)	TSHRMAPK1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL31142146	0.72	CNR2 (0.43)	—
	SCHEMBL24345245	0.70	—	—
	SCHEMBL15353266	0.67	CDK4 (0.38)	TSHRMAPK1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL13735287	0.66	—	—
	SCHEMBL24329965	0.64	CYP11B1 (0.57)	TSHRMAPK1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL31321057	0.64	CYP11B1 (0.57)	TSHRMAPK1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL28992835	0.63	MAPK1 (0.42)	TSHRMAPK1SMN1; SMN2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.