Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213806 | 0.82 | CASP3 (0.44) | GAAKMT2APTGS2MEN1POLB | |
| SCHEMBL11598523 | 0.71 | CDK5 (0.55) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL14030962 | 0.70 | GAA (0.58) | GAAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6522697 | 0.69 | GAA (0.52) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL10962827 | 0.69 | TDP2 (0.56) | GAAPOLBKDM4ECES1CASP3 | |
| SCHEMBL32680469 | 0.69 | TDP2 (0.56) | GAAPOLBKDM4ECES1CASP3 | |
| SCHEMBL11832606 | 0.68 | ALDH1A1 (0.41) | GAAKMT2AMEN1POLBDUSP3 | |
| Hydrochloric Acid SCHEMBL31218470 | 0.68 | TDP2 (0.54) | GAAPOLBKDM4ECES1CASP3 | |
| SCHEMBL7166848 | 0.67 | ALDH1A1 (0.49) | KMT2APTGS2MEN1KDM4ECYP3A4 | |
| SCHEMBL3520419 | 0.67 | KMT2A (0.50) | GAAKMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245729-A2 | Aromatic (poly)-sulfonimides and process for their preparation | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |