Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621372 | 0.85 | CYP3A4 (0.50) | CA12ALDH1A1CA2LMNACYP3A4 | |
| SCHEMBL24863821 | 0.85 | ALDH1A1 (0.50) | CA12ALDH1A1CA2LMNACYP3A4 | |
| SCHEMBL31615436 | 0.85 | ALDH1A1 (0.50) | CA12ALDH1A1CA2LMNACYP3A4 | |
| SCHEMBL30891540 | 0.83 | ACHE (0.48) | ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL21691192 | 0.83 | PARP1 (0.42) | HPGDALDH1A1CA14 | |
| SCHEMBL8100115 | 0.83 | CES2 (0.45) | CA12CA9CA14 | |
| SCHEMBL4457937 | 0.83 | ACHE (0.48) | ALDH1A1LMNAHSD17B10KCNH2 | |
| SCHEMBL10344176 | 0.83 | CYP1A2 (0.45) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL7514462 | 0.81 | FAAH (0.34) | LMNA | |
| SCHEMBL1585001 | 0.81 | ACHE (0.46) | ALDH1A1LMNAHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245729-A2 | Aromatic (poly)-sulfonimides and process for their preparation | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| EP-0245730-A1 | Process for the preparation of aromatic (poly)sulfones | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |