Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891540 | 1.00 | ACHE (0.48) | ACHEPARP1LMNAHDAC8HDAC6 | |
| SCHEMBL7520839 | 0.98 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 | |
| SCHEMBL7521244 | 0.98 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 | |
| SCHEMBL7139905 | 0.98 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 | |
| SCHEMBL1585001 | 0.98 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 | |
| SCHEMBL10775693 | 0.83 | HPGD (0.32) | LMNAHSD17B10ALDH1A1KCNH2 | |
| SCHEMBL29169693 | 0.82 | CYP1A2 (0.36) | ACHEHSD17B10ALDH1A1GAAMEN1 | |
| Toluene SCHEMBL28106985 | 0.79 | LMNA (0.52) | ACHELMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1584999 | 0.76 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 | |
| Lithium Ion SCHEMBL7521237 | 0.76 | ACHE (0.46) | ACHEPARP1LMNAHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117142916-B | Preparation method of allyl sulfone compound | 安徽金桐精细化学有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-117142916-A | Preparation method of allyl sulfone compound | 安徽金桐精细化学有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-110627693-B | Allyl sulfone compound and preparation method and application thereof | 南京工业大学 | 2021-06-04 | — | — | CN | claimed |
| CN-110627693-A | Allyl sulfone compound and preparation method and application thereof | 南京工业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-117142916-B | Preparation method of allyl sulfone compound | 安徽金桐精细化学有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-117142916-A | Preparation method of allyl sulfone compound | 安徽金桐精细化学有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | Oxford Drug Design Limited (GB) | 2023-10-31 | — | — | US | disclosed |
| CN-110627693-B | Allyl sulfone compound and preparation method and application thereof | 南京工业大学 | 2021-06-04 | — | — | CN | disclosed |
| WO-2021047674-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | 南京明德新药研发有限公司 | 2021-03-18 | — | — | WO | disclosed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-111743782-A | Powder-liquid type dental resin reinforced glass ionomer cement composition | 株式会社松风 | 2020-10-09 | — | — | CN | disclosed |
| CN-111743783-A | Double-paste type dental resin reinforced glass ion cement composition | 株式会社松风 | 2020-10-09 | — | — | CN | disclosed |
| US-7041714-B2 | Dental adhesive | TOKUYAMA CORPORATION (JP) | 2006-05-09 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1459726-A1 | ADHESIVES FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040077746-A1 | Adhesives for dental use | TOKUYAMA CORPORATION (JP) | 2004-04-22 | — | — | US | disclosed |
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| US-4764203-A | Herbicidal sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| US-4602084-A | Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component | CIBA-GEIGY CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077746-A1 | Adhesives for dental use | ICAM1, CDH1, VCAM1 | ACHE 737/4885PARP1 2727/4885LMNA 3337/4885 |
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | AARS1, NSUN3, GARS1 | ACHE 4392/4885PARP1 2614/4885LMNA 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.