Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612347 | 0.98 | MEN1 (0.58) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| SCHEMBL13988525 | 0.84 | MEN1 (0.67) | MEN1KMT2ARECQLSMN1; SMN2ACHE | |
| SCHEMBL20443877 | 0.80 | CASP2 (0.55) | — | |
| SCHEMBL12799428 | 0.77 | MEN1 (0.78) | MEN1KMT2ARECQLMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL1260787 | 0.76 | LMNA (0.40) | LMNAAPEX1SMN1; SMN2BLMPOLB | |
| SCHEMBL16316308 | 0.75 | MEN1 (0.48) | MEN1KMT2ARECQLLMNAAPEX1 | |
| SCHEMBL14108231 | 0.74 | HPGD (0.40) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL17735863 | 0.74 | FAAH (0.62) | — | |
| SCHEMBL7088407 | 0.74 | FAAH (0.62) | — | |
| SCHEMBL7088894 | 0.74 | FAAH (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661633-A | Method for preparing quaternary ammonium salts | THE DOW CHEMICAL COMPANY (US) | 1987-04-28 | — | — | US | disclosed |