Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.49 |
| ▸ | HEXA | P06865 | 1/20 | 0.47 |
| ▸ | HEXB | P07686 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778394 | 0.87 | HEXA (0.58) | PRKAG1PRKAA1PRKAB1HEXAHEXB | |
| SCHEMBL10772902 | 0.84 | PRKAG1 (0.48) | PRKAG1PRKAA1PRKAB1HEXAHEXB | |
| SCHEMBL28069481 | 0.73 | ALDH1A1 (0.51) | PRKAG1PRKAA1PRKAB1IKBKBKMT2A | |
| SCHEMBL11907360 | 0.72 | ATR (0.70) | MAP4K4CHEK1PRKDCATR | |
| SCHEMBL17178210 | 0.71 | PTGS2 (0.50) | KMT2APKMCA1CA2ALDH1A1 | |
| SCHEMBL5195843 | 0.71 | PTGDR2 (0.52) | PRKAG1PRKAA1PRKAB1KDM4EKMT2A | |
| SCHEMBL14358933 | 0.70 | HEXA (0.65) | HEXAHEXBKDM4EALDH1A1POLB | |
| SCHEMBL29106097 | 0.70 | CHEK1 (0.52) | PRKAG1PRKAA1PRKAB1KDM4EKMT2A | |
| SCHEMBL8975579 | 0.70 | ALDH1A1 (0.55) | KDM4EKMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL5192459 | 0.69 | PTGDR2 (0.53) | KDM4EPKMHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689328-A | CARBOXY-PYRIMIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |