Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918613 | 0.86 | GAA (0.68) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL8974906 | 0.86 | HSD17B10 (0.68) | ALDH1A1KDM4ERXFP1HPGDADORA1 | |
| SCHEMBL8975128 | 0.81 | HTT (0.48) | ALDH1A1MAPTKDM4ERXFP1MEN1 | |
| SCHEMBL8918577 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL3359383 | 0.74 | KDM4E (0.60) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL8917192 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL17747485 | 0.73 | ALDH1A1 (0.76) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL15286708 | 0.73 | ADORA1 (0.50) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL13914641 | 0.73 | ALDH1A1 (0.74) | ALDH1A1MAPTNPSR1KDM4ERXFP1 | |
| SCHEMBL13913746 | 0.72 | ADORA1 (0.80) | ALDH1A1MAPTNPSR1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |