Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772214 | 0.82 | STAT3 (0.77) | HTR1ASTAT3ADRB2CYP19A1 | |
| SCHEMBL10771960 | 0.81 | HTR1A (0.41) | HTR1APTGS2STAT3 | |
| SCHEMBL27673619 | 0.79 | HTR2A (0.59) | PTGS2HTR2AHTR2CHTR2BSTAT3 | |
| SCHEMBL10776224 | 0.79 | TUBB4A (0.51) | HTR1APTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL14722397 | 0.78 | STAT3 (0.47) | HTR2AHTR2CHTR2BSTAT3TUBB4A | |
| SCHEMBL2500546 | 0.78 | PTGS2 (0.68) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| SCHEMBL9253296 | 0.77 | HTR2A (0.60) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| SCHEMBL4464142 | 0.75 | HTR2A (0.75) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| SCHEMBL11335439 | 0.75 | HTR2A (0.58) | PTGS2HTR2AHTR2CHTR2BTUBB4A | |
| SCHEMBL5568951 | 0.74 | PTGS2 (0.63) | PTGS2HTR2AHTR2CHTR2BTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229944-A2 | Novel tetrahydroisoquinoline derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-07-29 | — | — | EP | disclosed |