Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979072 | 0.90 | GPR119 (0.41) | — | |
| Hydrochloric Acid SCHEMBL979545 | 0.88 | TDP1 (0.35) | F10BRD4HTR6 | |
| SCHEMBL978347 | 0.88 | TDP1 (0.35) | F10BRD4HTR6 | |
| SCHEMBL978165 | 0.86 | BRD4 (0.30) | BRD4 | |
| SCHEMBL1077942 | 0.64 | HTR2C (0.37) | HTR6 | |
| SCHEMBL3533847 | 0.61 | ALDH1A1 (0.35) | — | |
| SCHEMBL1078144 | 0.60 | CYP4F2 (0.52) | — | |
| SCHEMBL12813434 | 0.59 | GPR119 (0.57) | — | |
| SCHEMBL796332 | 0.59 | GRIN2D (0.55) | — | |
| SCHEMBL27150060 | 0.58 | ITGB3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454251-A1 | GPR119 AGONISTS | Eli Lilly and Company (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011008663-A1 | GPR119 AGONISTS | ELI LILLY AND COMPANY (US) | 2011-01-20 | — | — | WO | disclosed |