Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322435 | 0.85 | ALDH1A1 (0.56) | CRHBPCRHR2ALDH1A1NPC1RAB9A | |
| SCHEMBL27778044 | 0.84 | ALDH1A1 (0.51) | CRHBPCRHR2ALDH1A1NPC1RAB9A | |
| SCHEMBL18768957 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL10398568 | 0.78 | CRHBP (0.65) | CRHBPCRHR2ALDH1A1LMNACYP3A4 | |
| SCHEMBL4593938 | 0.75 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AMAPTSLC6A3 | |
| SCHEMBL19501289 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL29842802 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL19501287 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL10750775 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL2027905 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |