Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783421 | 0.84 | CRHBP (0.56) | ALDH1A1CRHBPCRHR2NPC1RAB9A | |
| SCHEMBL7322435 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CRHBPCRHR2NPC1RAB9A | |
| SCHEMBL27641824 | 0.81 | CRHBP (0.45) | ALDH1A1CRHBPCRHR2KDM4ECYP1A2 | |
| SCHEMBL27757187 | 0.80 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL18768957 | 0.79 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL2290 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL27641818 | 0.74 | CES2 (0.45) | ALDH1A1CRHBPCRHR2NPC1RAB9A | |
| SCHEMBL4593938 | 0.73 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AMAPTSLC6A3 | |
| SCHEMBL27831317 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CRHBPCRHR2KDM4ELMNA | |
| SCHEMBL2027905 | 0.73 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535315-A | Heterocyclic compounds useful as anabolic agents for livestock animals | PFIZER LTD (GB) | 2009-09-16 | — | — | CN | disclosed |