SCHEMBL1078427

SCHEMBL1078427

CC(C)CCC1=CCCC1=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.38
GSTP1 P09211 2/20 0.35
SORT1 Q99523 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HTR2C P28335 1/20 0.33
FNTA P49354 1/20 0.32
PGGT1B P53609 1/20 0.32
DHODH Q02127 1/20 0.32
CYP1A2 P05177 1/20 0.31
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
IDO1 P14902 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633992 0.89 GSTP1 (0.46) DAOGSTP1SORT1SMN1; SMN2HTR2C
SCHEMBL6898539 0.89 FNTA (0.39) DAOGSTP1SMN1; SMN2HTR2CFNTA
SCHEMBL6895221 0.87 FNTA (0.35) DAOGSTP1SMN1; SMN2HTR2CFNTA
SCHEMBL6902554 0.82 GSTP1 (0.32) GSTP1CYP1A2
SCHEMBL6902367 0.79 PTPN1 (0.34) DAOGSTP1SORT1CYP1A2
SCHEMBL1044406 0.77
SCHEMBL31436467 0.77 FNTA (0.40) GSTP1FNTAPGGT1B
SCHEMBL31485230 0.75 GSTP1 (0.42) GSTP1SMN1; SMN2FNTAPGGT1B
SCHEMBL1150883 0.73 ACHE (0.36) DAOGSTP1
SCHEMBL28163589 0.73 DHODH (0.33) SMN1; SMN2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109309-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2022-06-08 EP disclosed
EP-3109309-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2022-06-08 EP disclosed
EP-3109308-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2022-06-01 EP disclosed
EP-3109308-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2022-06-01 EP disclosed
EP-3901129-A1 METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS L'OREAL (FR) 2021-10-27 EP disclosed
US-10995051-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid L'OREAL (FR) 2021-05-04 US disclosed
EP-3109307-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2021-03-31 EP disclosed
EP-3109307-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2021-03-31 EP disclosed
US-10654788-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid L'OREAL (FR) 2020-05-19 US disclosed
US-20200131108-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID L'OREAL (FR) 2020-04-30 US disclosed
WO-2013109798-A2 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2013-07-25 WO disclosed
WO-2013109798-A2 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2013-07-25 WO disclosed
US-8378147-B2 Process for producing a 2-alkyl-2-cycloalkene-1-one KAO CORPORATION (JP) 2013-02-19 US disclosed
US-20110040127-A1 PROCESS FOR PRODUCING A 2-ALKYL-2-CYCLOALKEN-1-ONE KAO CORPORATION (JP) 2011-02-17 US disclosed
EP-2269971-A1 PROCESS FOR PRODUCING A 2-ALKYL-2-CYCLOALKENE-1-ONE Kao Corporation (JP) 2011-01-05 EP disclosed
US-6833481-B2 Catalytic dehydrative isomerization TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-12-21 US disclosed
US-20030109755-A1 Process for producing 2-alkyl-2cyclopentenones TAKASAGO INTERNATIONAL CORPORATION 2003-06-12 US disclosed
EP-1316541-A1 Process for producing 2-alkyl-2-cyclopentenones Takasago International Corporation (JP) 2003-06-04 EP disclosed
CN-1421429-A Process for producing 2-alkyl-2-cyclopentenone TAKASAGO PERFUMERY CO LTD (JP) 2003-06-04 CN disclosed
US-4329508-A Process for making alkyl cyclopentenones SCM CORPORATION (US) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10654788-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid HSD17B12, FASN, AKR1C3 DAO 273/4885GSTP1 2982/4885SORT1 4254/4885
US-20110040127-A1 PROCESS FOR PRODUCING A 2-ALKYL-2-CYCLOALKEN-1-ONE CYP1B1, GRK1, CYP2J2 DAO 2077/4885GSTP1 1616/4885SORT1 4857/4885
US-10995051-B2 Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid CYP8B1, HAAO, HSD17B12 DAO 395/4885GSTP1 3431/4885SORT1 3612/4885
US-20030109755-A1 Process for producing 2-alkyl-2cyclopentenones HSD3B2, DHPS, HSD3B1 DAO 2558/4885GSTP1 2717/4885SORT1 4804/4885
US-20200131108-A1 METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID CYP8B1, HAAO, HSD17B12 DAO 395/4885GSTP1 3431/4885SORT1 3612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.