Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470803 | 0.86 | LTA4H (0.51) | LTA4HTAAR1KMT2ALMNAIDO1 | |
| Hydrochloric Acid SCHEMBL9467955 | 0.81 | TAAR1 (0.66) | LTA4HTAAR1LMNAIDO1 | |
| SCHEMBL29474956 | 0.81 | TAAR1 (0.64) | TAAR1ABCB1LMNAIDO1KCNH2 | |
| SCHEMBL621779 | 0.81 | HTR1A (0.58) | LTA4HTAAR1ABCB1LMNAIDO1 | |
| SCHEMBL852646 | 0.81 | TAAR1 (0.64) | TAAR1ABCB1LMNAIDO1KCNH2 | |
| SCHEMBL3153666 | 0.80 | KMT2A (0.56) | LTA4HTAAR1KMT2AIDO1SLC5A1 | |
| SCHEMBL7282070 | 0.80 | LTA4H (0.62) | LTA4HTAAR1ABCB1TDP1LMNA | |
| SCHEMBL1682187 | 0.80 | LTA4H (0.52) | LTA4HTAAR1IDO1SLC5A1SLC5A2 | |
| SCHEMBL16321443 | 0.79 | ALDH1A1 (0.56) | LTA4HTAAR1KMT2ALMNAIDO1 | |
| SCHEMBL27462498 | 0.79 | LTA4H (0.58) | LTA4HTAAR1ABCB1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112588-B1 | 4-HYDROXY-ALPHA-ETHYL BENZHYDROLES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-11-11 | — | — | EP | claimed |
| EP-0112588-A2 | 4-Hydroxy-alpha-ethyl benzhydroles, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | claimed |
| EP-0112588-B1 | 4-HYDROXY-ALPHA-ETHYL BENZHYDROLES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-11-11 | — | — | EP | disclosed |
| EP-0112588-A2 | 4-Hydroxy-alpha-ethyl benzhydroles, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |