Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790366 | 0.86 | LTA4H (0.49) | LTA4HIDO1TAAR1SLC5A1SLC5A2 | |
| SCHEMBL621779 | 0.84 | HTR1A (0.58) | LTA4HIDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL3153666 | 0.83 | KMT2A (0.56) | LTA4HIDO1TAAR1SLC5A1SLC5A2 | |
| SCHEMBL7282070 | 0.83 | LTA4H (0.62) | LTA4HIDO1TAAR1SLC5A1SLC5A2 | |
| SCHEMBL1682187 | 0.83 | LTA4H (0.52) | LTA4HIDO1TAAR1SLC5A1SLC5A2 | |
| SCHEMBL27462498 | 0.81 | LTA4H (0.58) | LTA4HIDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL16321443 | 0.81 | ALDH1A1 (0.56) | LTA4HIDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL17820 | 0.80 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1LMNA | |
| SCHEMBL30829273 | 0.80 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1LMNA | |
| SCHEMBL6245371 | 0.80 | RXRA (0.63) | KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236934-A | Angiotensin inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-4079075-A | Primary alkyl esters as mediums for oxidations by phase-transfer catalyzed hypohalites | THE DOW CHEMICAL COMPANY (US) | 1978-03-14 | — | — | US | disclosed |