Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777601 | 0.88 | PSIP1 (0.67) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL798585 | 0.79 | PSIP1 (0.56) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL576918 | 0.78 | KEAP1 (0.63) | PSIP1ALDH1A1HSD11B1L3MBTL1KEAP1 | |
| SCHEMBL10629823 | 0.78 | PSIP1 (0.61) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL1357929 | 0.77 | HSD11B1 (0.55) | PSIP1ALDH1A1HSD17B10HSD11B1L3MBTL1 | |
| SCHEMBL10789315 | 0.77 | PSIP1 (0.54) | PSIP1HSD11B1L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL10626503 | 0.76 | HDAC1 (0.65) | PSIP1ALDH1A1HSD11B1L3MBTL1KEAP1 | |
| SCHEMBL2454944 | 0.76 | PSIP1 (0.58) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL3394881 | 0.76 | PSIP1 (0.52) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL6138753 | 0.76 | HSD11B1 (0.53) | PSIP1ALDH1A1HSD17B10HSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136878-B1 | FUNGICIDAL SULFONAMIDE DERIVATIVES | CHEVRON RESEARCH COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4511735-A | N-/ALKYLTHIO/-2-/ALKYLSULFONYL/ETHANESULFONAMIDES | CHEVRON RESEARCH COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0136878-A2 | Fungicidal sulfonamide derivatives | CHEVRON RESEARCH COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |