Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394881 | 0.86 | PSIP1 (0.52) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL777601 | 0.85 | PSIP1 (0.67) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4728760 | 0.85 | KEAP1 (0.54) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL55285 | 0.84 | CA1 (0.44) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL8557785 | 0.83 | HDAC1 (0.56) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL7390512 | 0.83 | HDAC1 (0.56) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL576918 | 0.80 | KEAP1 (0.63) | PSIP1HSD11B1ALDH1A1L3MBTL1HTR6 | |
| SCHEMBL10629823 | 0.80 | PSIP1 (0.61) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL491272 | 0.80 | PSIP1 (0.61) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL426162 | 0.79 | ALDH1A1 (0.52) | HSD11B1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175397-B | A kind of hydrobromic acid eletriptan synthetic method | 上海现代哈森（商丘）药业有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-105175397-A | Synthesis method of eletriptan hydrobromate | SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | claimed |
| CN-104531397-A | Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof | HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-102126995-A | Improved preparation process of phenyl vinyl sulfone | TAIZHOU CITY HWASUN PHARMACUETICAL AND CHEMICAL CO LTD | 2011-07-20 | — | — | CN | claimed |
| EP-1256608-B1 | Inkjet inks | HEWLETT PACKARD CO (US) | 2005-11-30 | — | — | EP | claimed |
| EP-1256608-A2 | Inkjet inks | Hewlett-Packard Company (US) | 2002-11-13 | — | — | EP | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-20240277683-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-08-22 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-11851434-B2 | Substituted pyrazolo[1,5-A]pyrazine compounds as ret kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-12-26 | — | — | US | disclosed |
| EP-3571203-B1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRAZINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11420963-B2 | Rebamipide prodrugs, preparation method and use thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2022-08-23 | — | — | US | disclosed |
| CN-108349969-B | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阵列生物制药公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-0101199-A1 | Beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-02-22 | — | — | EP | disclosed |
| US-4428937-A | OXAPENICILLINS; BETA-LACTAMASE INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-01-31 | — | — | US | disclosed |
| EP-0066415-A2 | N-(arylthioalkyl)-N'-(aminoalkyl)ureas | A.H. ROBINS COMPANY, INCORPORATED (US) | 1982-12-08 | — | — | EP | disclosed |
| US-4297345-A | DEOXY- AND ISODEOXYCLAVULANIC ACID SYMERGISTIC WITH PENICILLIN AND CEPHALOSPORIN ANDITIOTICS | BEECHAM GROUP LIMITED (GB) | 1981-10-27 | — | — | US | disclosed |
| US-4232005-A | OXAPENICILLINS; SYNERGISTIC | BEECHAM GROUP LIMITED (GB) | 1980-11-04 | — | — | US | disclosed |
| US-4098897-A | ANTI BACTERIAL AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277683-A1 | COMPOUNDS | SLC10A1, ABCB11, REN | PSIP1 2041/4885HSD11B1 56/4885ALDH1A1 951/4885 |
| US-11851434-B2 | Substituted pyrazolo[1,5-A]pyrazine compounds as ret kinase inhibitors | RET, BRAF, ROR1 | PSIP1 1501/4885HSD11B1 2467/4885ALDH1A1 3241/4885 |
| US-11420963-B2 | Rebamipide prodrugs, preparation method and use thereof | SI, CYP2A7, MLN | PSIP1 1563/4885HSD11B1 854/4885ALDH1A1 908/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | PSIP1 1838/4885HSD11B1 41/4885ALDH1A1 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.