Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271963 | 0.75 | NPSR1 (0.48) | ENPP3MAPT | |
| SCHEMBL7892961 | 0.71 | NPSR1 (0.48) | CA2CA1CA4CA7TP53 | |
| SCHEMBL8476187 | 0.68 | PTGS2 (0.51) | MAOBCA2CA1CA4CA7 | |
| SCHEMBL29808069 | 0.65 | CA2 (0.58) | MAOBCA2CA1CA9CA12 | |
| SCHEMBL11483128 | 0.63 | MAOB (0.52) | ENPP3MAOBCA2CA1CA4 | |
| SCHEMBL6175116 | 0.63 | ALDH1A1 (0.55) | MAOBMAPT | |
| SCHEMBL11465125 | 0.63 | MAOB (0.52) | ENPP3MAOBCA2CA1CA4 | |
| SCHEMBL11150063 | 0.63 | AKR1B1 (0.48) | MAOBCA2CA1TP53CA9 | |
| SCHEMBL11105555 | 0.63 | MAOB (0.56) | MAOBCA2CA1CA4CA7 | |
| SCHEMBL17441666 | 0.63 | LDHA (0.62) | CA2CA1CA4CA7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051215-A2 | Methods and intermediates for the synthesis of 3-aryl-3-hydroxy-phthalimidines | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0051215-B1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF 3-ARYL-3-HYDROXY-PHTHALIMIDINES | USV PHARMACEUTICAL CORPORATION (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4331600-A | 3-/HALOSULFONYL OR SULFAMYLPHENYL/PHTHALIMIDINE, HYPOTENSIVE AGENTS, DIURETICS | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| EP-0051215-A2 | Methods and intermediates for the synthesis of 3-aryl-3-hydroxy-phthalimidines | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051217-A1 | Oxidation process | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |